A prince named Naveen (Bruno Campos) from the land of Maldonia is transformed into a frog by the evil scheming voodoo magician Dr. Facilier (Keith David). The frog prince mistakes a girl named Tiana (Anika Noni Rose) for a princess and has her kiss him to break the spell. However, the kiss doesn't break the spell, but instead turns Tiana into a frog as well. Together, the two of them must reach the good voodoo priestess of the Bayou, Mama Odie, while befriending a trumpet-playing alligator and a hopelessly romantic firefly along the way.